Men's HealthAsad K. Niazi, MD, MPH
Board Certification
Internal Medicine (ABIM)
Alma Mater
Texas Tech University – Foster School of Medicine
Sexual Health
Daily tablet
First order: $90
Larger supplies unlock the lowest per-dose pricing. Automatic refills – pause, delay or cancel anytime – just make those changes at least 48 hours before your next refill date.
Daily support for blood flow, training, and recovery.
Larger supplies unlock the best per-dose pricing.
$90 total
Larger supplies unlock the lowest per-dose pricing.
Check Eligibility$175 total
Larger supplies unlock the lowest per-dose pricing.
Save 3%Check Eligibility$270 total
Larger supplies unlock the lowest per-dose pricing.
Save 25%Check EligibilityStart
Answer a few questions about your health and goals.
⏱ 5-10 minutes
Review
They decide whether treatment is appropriate. No video visit required in 41 states.
⏱ <4 business hours
Delivered
One of our trusted pharmacy partners discreetly ships your medication to your doorstep.
⏱ <1 week*
*Timelines shown reflect our average turnaround times and are not guaranteed.
You've got a solid program, a real pre-workout stacked, and you're still leaving gains on the table. Here's the bottleneck: your blood vessels.
Daily 5mg tadalafil blocks PDE5, the enzyme that constricts blood vessels. That means more nitric oxide signaling, wider vessels, and more oxygen and nutrients reaching working muscle — before, during, and after your session.
It's not a hack. It's physiology.
Better blood flow. Bigger pumps. Faster recovery. Tap a pin to see what daily tadalafil does for each.
Tadalafil works by blocking PDE5, the enzyme that breaks down cGMP in smooth muscle cells. More cGMP means more nitric oxide activity, wider vessels, and more delivery to working tissue.
This isn't bro science. It's peer-reviewed research from journals including JCEM, Clinical and Translational Science, and British Journal of Clinical Pharmacology.
Tadalafil amplified salivary testosterone AND cortisol responses to maximal exercise vs. cortisol-only rise in placebo.
Di Luigi, L., et al. (2008). J Clin Endocrinol Metab, 93(9), 3510–3514.
Short-term daily PDE5 treatment increased skeletal muscle protein synthesis and reduced fatigue in humans. The protein synthesis response was of similar magnitude to 100–200 mg/week testosterone injection.
Sheffield-Moore, M., et al. (2013). Clin Transl Sci, 6(6), 463–468.
PDE5 inhibition reduced muscle damage markers and improved endurance over 4 weeks.
Venckunas, T., et al. (2019). J Appl Physiol, 127(1), 48–58.
Tadalafil reduced arterial stiffness and systolic blood pressure during recovery from exercise in humans.
Rosano, G. M., et al. (2006). Br J Clin Pharmacol.
4.8 average. Patients love us. And we work hard to earn it.
Men's HealthBoard Certification
Internal Medicine (ABIM)
Alma Mater
Texas Tech University – Foster School of Medicine
LongevityBoard Certification
Family Medicine (ABFM)
Alma Mater
Xavier University School of Medicine
LongevityBoard Certification
Family Medicine (ABFM)
Alma Mater
Xavier University School of Medicine
Men's HealthBoard Certification
Physical Medicine and Rehabilitation (ABPMR)
Alma Mater
Lake Erie College of Osteopathic Medicine
Oversight
Physician reviewed
Dose
Tadalafil Daily is an erectile dysfunction treatment that allows you to get an erection when you need one — without timing a tablet beforehand. Effective in over 85% of men.
Frequency
Daily tablet
Included
Medication, supplies, expedited shipping
Ignite combines Tadalafil and Sildenafil in one powerful compounded rapid-dissolving tablet — the fast action of Sildenafil with the long-lasting effects of Tadalafil.
Starting at $125
Trimix is a triple-compound injectable medication (alprostadil, papaverine, and phentolamine) that delivers the most reliable results for ED. Ideal for men who haven't responded well to oral medications. Second and subsequent refills $200 per 30-day supply.
Starting at $160
Related Reading
Deeper dives from our editorial team — pricing, dosing, and the research behind it.
*Tadalafil is an FDA-approved medication for the treatment of erectile dysfunction. The information on this page is for educational purposes only and does not substitute for professional medical advice. Individual results may vary.
1 Porst, H., et al. (2006). Evaluation of the efficacy and safety of once-a-day dosing of tadalafil. European Urology, 50(2), 351–359.








